David Martin

david

CHORI, USA

Regulated gene expression underlies cell differentiation and development in higher eukaryotes. David Martin, MD, Senior Scientist at CHORI and Chair of the Center for Genetics, is interested in this process because of its fundamental role in creating phenotypic diversity in genotypically identical cells and organisms, and because it is disrupted in cancer cells. This interest has led him to investigate epigenetic inheritance and germline epimutation in mammals.

Dr. Martin’s current interests are the extent and mechanism of epigenetic inheritance in mammals, the development of models of stable epigenetic inheritance, and the disruption of epigenetic stability in senescence and cancer.